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Serbian Journal of Experimental and Clinical Research 2009, vol. 10, iss. 1, pp. 27-31
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article language: English
Original Scientific Paper
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Efficiency of argon laser trabeculoplasty in open angle glaucoma therapy
AbstractIntroduction. Argon laser trabeculoplasty (ALT) is a method for the reduction of intraocular pressure (IOP) that involves applying a laser to the area of the trabecular meshwork of the chamber angle in patients with open angle glaucoma. Aims. To evaluate the efficiency and safety of ALT in open angle glaucoma therapy. Material and method. A prospective examination of 84 eyes from 49 patients who were primarily treated with medications but did not achieve sufficient control of their IOP. Prior to ALT, a detailed ophthalmology check had been performed. After the treatment, follow-up visits were scheduled at 24 hours, 1 month, 3 months, 6 months, 1 year, 2 years and 4 years. The success of the treatment was defined by IOP≤21 mmHg, with no further progression of disc or visual field changes. Results. The average value of IOP before ALT was 25.28 ± 1.56 mmHg. After 24 hours, 19 eyes (23.5%) had a transitory rise in the IOP of < 4 mmHg. One month after the treatment the average IOP was 19.68 ± 2.26 mmHg, and 3 months later it was 18.01 ± 1.87 mmHg. At 6 months it was 17.4 ± 1.65 mmHg, at 1 year 17.96 ± 2.44 mmHg, at 2 years 18.22 ±2.65 mmHg and at 4 years 18.49 ± 2.95 mmHg. The target pressure of ≤ 21 mmHg was achieved after 1 month in 77.8% of the patients, after 3 months in 93.8%, after 6 months in 93.8%, after 1 year in 80.2%, after 2 years in 75.3% and after 4 years in 66.7%. Two years after the treatment, a filtering surgery was performed in one case (1.2%), due to an unreduced IOP . At the end of the fourth year after the intervention, the number of examined eyes was 73, and a filtering surgery was performed for the unreduced IOP on 8 eyes (9.9%). The average reduction in IOP one year after the intervention was 7.32 ± 2.84 mmHg, after 2 years 7.16 ± 2.98 mmHg, and after 4 years 6.84 ± 3.33 mmHg (p<0.01). Conclusion. ALT is a safe and efficient method for IOP reduction in patients with open angle glaucoma, which can postpone filtering surgery to a great extent.
Keywords
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